Untitled Document

WCUP funded Research Project


Grant Code(s) & date Awarded

PhD/19/2013 14th August 2013

Title

Investigation into possible natural products /herbal based therapeutics intervention with special reference to extract of Ceylon green tea on the functional status of patients with Duchene Muscular Dystrophy and Spinal Muscular Atrophy in relation to their genetic mutations.

Student Name

W.H.M.D.N.B Wijekoon

Supervisors

Prof. Ranil De Silva Department of Anatomy

Abstracts

  • Wijekoon DNB, Ratnayake PD, Suriyakumara SVT, Gonawala BL, Dalal A, Sebahattin C, Nazarian J, Hoffman E, De Silva KRD. Duchenne Muscular Dystrophy in Monozygotic Twins: Seventh Report Worldwide. 8th International Brain Research Organization (IBRO) Canadian School of Neuroscience, Montreal, May 14-28, 2014.

  • Wijekoon, D.N.B., Gamage, R., Ratnayake, P.D., Gonawala, B.L., Jayasinghe, M.C., Nazarian, J., Hoffman, E., De Silva, K.R.D. 2012. Performance in activities of daily living in children with Duchenne Muscular Dystrophy: A Sri Lankan perspective. Annals of Neurosciences. Vol 19; Sup: 45

  • Gonawala, B.L., Gamage, R., Ratnayake, P.D., Wijekoon, D.N.B.,Jayasinghe, M.C., Nazarian, J., Hoffman, E., De Silva, K.R.D. 2012.Territorial localization and familial genetic transmission of Duchenne Muscular Dystrophy (DMD) and Spinal Muscular Atrophy (SMA): A Sri Lankan outlook towards genetic analysis. Annals of Neurosciences. Vol 19; Sup: 43

Publications

  • Nalaka Wijekoon, Pyara Ratnayake, Ranjani Gamage, Vindika Suriyakumara, Lakmal Gonawala, Ashwin Dalal, Akshay Anand, Dhammika Amarathunga, Cirak Sebahattin, Javad Nazarian, Eric Hoffman, Ranil de Silva. Genotype-phenotype analysis of Duchenne and Becker muscular dystrophy in two South Asian populations: A study protocol. Submitted to PLOS Currents Muscular Dystrophy

  • Akshay Anand, Rahul Tyagi, Nalaka Wijekoon, K. Ranil D. De Silva,. Dystrophin Induced Cognitive Impairment and its Molecular Mechanisms. Submitted

International Presentations (Oral)

  • Wijekoon, D.N.B., Amarathunga, D, De Silva, K.R.D. 2012. Statistical analysis of the relationship between consanguineous marriages and the incidence of Spinal Muscular Atrophy (SMA). Presented at Visiting Lecture Team Programme, International Brain Research Organization, organized by the Faculty of Medical Sciences, University of Sri Jayewardenepura, Sri Lanka.

International Presentations (Poster)

  • Wijekoon DNB, Ratnayake PD, Suriyakumara SVT, Gonawala BL, Dalal A, Sebahattin C, Nazarian J, Hoffman E, De Silva KRD. Duchenne Muscular Dystrophy in Monozygotic Twins: Seventh Report Worldwide. 8th Canadian Association for Neuroscience meeting 25- 28 May, Montreal.

  • Wijekoon, D.N.B., Gamage, R., Ratnayake, P.D., Gonawala, B.L., Jayasinghe, M.C., Nazarian, J., Hoffman, E., De Silva, K.R.D. 2012.Performance in activities of daily living in children with Duchenne Muscular Dystrophy: A Sri Lankan perspective. Presented at XXX Annual Conference of Indian Academy of Neurosciences(IAN), Amritsar, India.