Centre for Dengue Research

DCR 1 DCR 2 dcr 3
The CDR was established in September 2012 by a cabinet directive in the Faculty of Medical Sciences, University of Sri Jayawardenapura.

Dengue viral infections are the most important mosquito borne virus infection in the world causing significant morbidity and mortality worldwide. It is estimated that 390 million dengue infections occur annually, resulting in approximately 96 million clinically apparent infections predominantly in the resource poor developing countries.

CDR Board of Management

The CDR’s Board of Management will consists from the following members of the core departments of the University of Sri Jayewardenepura.

Department of Microbiology,Faculty of Medical Sciences : Dr. Neelika Malavige (Director of CDR)
Department of Geography, Faculty of Humanities & Social Sciences: Prof. Krishan Deheragoda
Department of Family Medicine, Faculty of Medical Sciences: Dr. Chandima Jeewandara
Department of Community Medicine, Faculty of Medical Sciences: Dr. Vathsala Jayasuriya
Bursar: University of Sri Jayewardenepura

Visiting Professors attached to the CDR

Prof. Grahm Ogg Prof. Graham Ogg
University of Oxford
Prof .Ng Lee Prof. Ng Mah Lee, National University of Singapore
Prof. Marilyn O'Hara Prof. Marilyn O’Hara
Prof. Nicole Zitzmann Prof. Nicole Zitsmann
University of Oxford
Dr. Joanna Miller Dr. Joanna Miller
University of Oxford

Publications in high impact factor international journals

(Feb 2015 to Feb 2016)

1.Kamaladasa A, Wickramasinghe N, Adikari TN, Gomes L, Shyamali NL, Salio M, Cerundolo V, Ogg GS, Malavige G.N.: Expansion of highly activated iNKT cells with altered phenotype in acute dengue infection. Clin Exp Immunol. 2016 Feb 13: Impact factor 3.1

2.Jeewandara C, Gomes L, Paranavitane SA, Tantirimudalige M, Panapitiya SS, Jayewardene A, Fernando S, Fernando RH,, Prathapan S, Ogg GS, Malavige GN. Change in Dengue and Japanese Encephalitis Seroprevalence Rates in Sri Lanka. PLoS One. 2015 Dec 22;10(12) : Impact factor: 3.6

3.Narmada Adikari T, Gomes L, Wickramasinghe N, Salimi M, Wijesiriwardana N, Kamaladasa A, Narangoda Liyanage AS, Ogg GS, Malavige GN. Dengue NS1 antigen contributes to disease severity by inducing IL-10 by monocytes. Clin Exp Immunol. 2015 Dec 1: Impact factor: 3.1

4.Malavige G.N., Ogg G.S. Role of skin homing T cells in acute dengue infection. Annals of Translational Medicine. Ann Transl Med 2015;3(17):252.

5.Jeewandara C, Adikari T.N., Gomes L, Fernando S., Fernando R.H., Perera M.K.T., Ariyarante D., Kamaladasa A, Salimi M, Prathapan S, Ogg G.S., Malavige G.N. Functionality of dengue virus specific memory T cell responses in individuals who were hospitalized or who had mild or subclinical dengue infection. PLoS Negl Trop Dis. 2015 Apr 13;9(4): Impact factor: 4.6

6.Jeewandara C, Gomes L, Wickramasinghe N, Gutowska-Owsiak D, Waithe D, Paranavitane SA, Shyamali NL, Ogg GS, Malavige GN.  Platelet activating activating factor contributes to vascular leak in acute dengue infection. PLoS Negl Trop Dis. 2015 Feb 3;9(2):e0003459. : Impact factor: 4.6